From biological weapon to cosmetic product is crazy
It saved my life essentially. I was getting 16 migraines a month now I get zero.
That’s amazing. What part of you was paralyzed to reduce the headaches?
My wife got this done. It was over 150 individual injections in her jaw, head, and neck.
It has been absolutely life changing for her following years of constant migraines. She was able to come off of nine separate medications as a result too.
Yikes, but worth it!
In my graduate neurology class, we learned how it works and that affected nerves can pass it along to adjacent nerves, disabling them as well. This takes multiple doses over time, so one or two treatments is not a huge concern. The professor then told us how shocked he was to learn that 15 year olds are getting injections.
The absolute coolness that is science and stuff amazes me! We saw a deadly poison, studied the shit outta it, now keep it and use it like a pet! It’s really neat!
All those glp-1 agonists that are all the rage right now are because scientists recognized the gila lizard can go long periods without eating while keeping its blood sugar stable and studied its venom
The current drugs like ozempic are synthetic though, no actual gila venom
Also fun fact: the guy that discovered the effect figured it out in the early 90s and actually patented it himself because for years no one was interested. Pharmaceutical industry was apparently “disinterested” and it wasn’t moved forward until 2002 (exenatide/byetta, a precursor to more efficacious drugs like tirzepatide/zepbound/mounjaro, which coincidentally made Eli Lilly the most valuable drug company in the world. Another fun fact is that Lilly partnered with another smaller company to make exenatide then Lilly dissolved the partnership in 2011, allowing the smaller company to keep the rights, likely because they saw the opportunity for the next steps)
If they develop a special one for men it should be Bro-tox.
Cut to Clavicular injecting it straight in to his nuts for some reason
Not just cosmetic, I believe it’s used to treat migraines and possibly other issues. Crazy stuff.
Dose makes the poison. Even the most toxic substance known to man can have benefits in a small enough dose.
If you ingest antifreeze, the cure is a measured amount of alcohol to counter the effects. The poison of my poison is my cure.
Same with methanol poisoning from tainted or improperly made alcohol beverages . The treatment is to drink proper alcohol beverages.
A few billionths of a single gram in a muscle will kill you. That’s fucking nuts that it’s used on people.
I was a part of the noburp community on the old site. In the last decade it’s been used to cure that. The body metabolizes it after about 6 months, but having that assistance often helps build the muscle memory and people can usually burp after that. I personally had it done twice and can still do small burps at last, and my daughter (toddler, born very prematurely) had it done at the beginning of the year. Her physical medicine doctor mentioned it as a possibility, and when I told him about the burping thing he basically equated Botox in the medical community with Windex in My Big Fat Greek Wedding
It was strange finding out that other people had the same issue
I would strongly suggest getting the treatment if you can! It’s a super simple procedure.
Luckily mine is only semi no burp; I can force it out with some effort. My theory is it’s because I played a wind instrument.
What’s the symptoms/consequences of not being able to burp?
The main ones you see almost universally are
- excessive flatulence (it’s gotta come out somewhere),
- bloating comparable with pregnancy (usually equivalent to what you’d see after several months in, but occasionally people look full term!)
- Weird gurgling noises in the throat
There are also things like hiccups, hypersalivation, constipation, and things like that that are common but not guaranteed.
My daughter has been pretty underweight for a while. I realized she’s had massive farts, and a bit of a big belly given the rest of her relatively small size. She was super hard to burp as an infant (that varies a lot in adults with the condition) and it pretty much stopped after a while. Basically the bloat kills the appetite.
The estimated human median lethal dose of type A toxin is 1.3–2.1 ng/kg intravenously or intramuscularly, 10–13 ng/kg when inhaled, or 1 μg/kg when taken by mouth
fuuuuuck thats… terrifying.
Fuck that’s crazy, its lethal dose by mouth is LSD’s standard dose by mouth 😂
What’s the dosage to get really, really fucking high??
2-3 ug/kg
Beyond that I don’t think even has any recreational value
I meant the Botox, lol
