Reaper is definitely the way to go. While it is not FOSS I feel it has the spirit of Linux. It is extremely customisable and flexible and it has all the features you expect from a good DAW.
The real issue is finding instrument and effect plugins that work on Linux. The popular ones are all windows or Mac only because they depend on DRM control software that doesn’t work on Linux.




I would be interested in any resources you have on improving latency with pipework. Windows has the ASIO driver which gives direct access to the Audi interface. I didn’t think pipewire was able to match it, but I’ll be glad to be wrong.
I took a brief looked at yabridge a while ago, but struggled. Sounds like I should revisit it.