Bottles only recently had a small update to make it less janky. Their team is working on a complete overhaul, Bottles Next.
To be honest, I’ve yet to find a program that doesn’t have a flatpack equivalent (eg OnlyOffice for Microsoft Word) or flatpack version (eg Firefox). But just in case, I have WineCharm installed (Wine GUI)
Seconding IRC. As a Bazzite user I use Konversation to access it.